But she warned that the tea didnt work for everyone and that taking the extract could interfere with regular chemotherapy. 4. Read reviews and buy NOW Supplements, Silymarin Milk Thistle Extract 300 mg with Artichoke and Dandelion, Double Strength, Supports Liver Function, 100 Veg Capsules at Target. To date, there are rapidly spreading new variants of concern of SARS-CoV-2, the United Kingdom (B.1.1.7), the South African (B.1.351) or Brasilian (P.1) variant. Researchers need to see if dandelion will work in people. When the cultured cells were challenged with the spike D614 and its variants, the binding affinity of the spike to the surface ACE2 was increased by about 1.5-fold and 3-4-fold with the D614G and N501Y mutations, respectively. Washington, DC Pharmaceuticals | Free Full-Text | New Approaches on the Anti Quack cure or Covid hope? Six science-backed foods that fight Covid Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics. Despite being considered a stubborn weed, dandelion contains powerful compounds that benefit the body. On the day of the Dec. 6 runoff, armed groups of Black Panthers were reportedly patrolling certain voting locations in Georgia. Black Americans are not descended from people who were taken from Africa to be enslaved. Sofia, Sofia City, Bulgaria Weather - The Weather Channel 32. 14. Dandelion Powder. We use your sign-up to provide content in ways you've consented to and to improve our understanding of you. But this study was not well designed. Biomed Pharmacother. Furthermore, on October 5 . Please enable it to take advantage of the complete set of features! Some people may have an allergic reaction from touching dandelion. The photograph shows a list of herbs and is titled . Dandelion extract inhibits SARS-CoV-2 in vitro. Discovery of diminazene as a dual inhibitor of SARS-CoV-2 human host proteases TMPRSS2 and furin using cell-based assays. 2021 Oct;142:112011. doi: 10.1016/j.biopha.2021.112011. It is not certain whether dandelion is effective in treating any medical condition. About Sibley Memorial Hospital Because dandelion tea has such potent ingredients, you should consult with your doctor before taking it or any other supplement. Native Americans also boiled dandelion in water and took it to treat kidney disease, swelling, skin problems, heartburn, and upset stomach. Fresh dandelion root: two to eight grams daily, Dandelion root powder: Three to four grams mixed with 150 millilitres of warm water, Dandelion tea infusion: One tablespoon of chopped root mixed with 150 millilitres of hot water for 20 minutes, Fresh root extract: One to two tablespoons daily, Dried dandelion extract: 0.75 to 1.0 grams daily. CSIR Study Finds Extracts of Velvet Leaf Can Prevent Viral - News18 Home of the Daily and Sunday Express. 7. Natural health products may well provide a potential nontoxic therapeutic alternative to conventional system therapy in the treatment of CMML, and one that also provides an improved quality-of-life. Air purifiers with HEPA filtration efficiently capture particles the size of (and far smaller than) the virus that causes COVID-19, so the answer is yes. Control blood sugar Bethesda, MD 20894, Web Policies CDC puts Sweden and 2 other places on 'high' risk list for Covid-19 - CNN Cho SY,Park JY, Park EM, et al. A study that showed the extract effective in killing 95% of colon cancer cells in 48 hours looked atcells in a petri dish, not in the human body. How to get rid of visceral fat: Cortisol may increase the belly fat, How to lose visceral fat: How many steps you must walk daily, High blood pressure: Lesser-known ways to reduce hypertension risk, Heart attack: Dandelion is a powerful plant rich in vitamin to reduce your risk, Heart attack: Dandelion can be made into a tea or in pill form to reap the many health benefits, Diabetes type 2: Five signs in the morning your blood sugar is high, How to live longer: A tipple a day could cut death risk says study, Heart attack symptoms: Five 'unusual' signs of heart disease on skin, Heart attack symptoms: The subtle warning sign on your lips. 33. May 23, 2013 (AP). Lab studies showed that papaya leaf extracts have antibacterial effects. So far, there have not been any quality scientific studies on dandelion. Compilation of the top interviews, articles, and news in the last year. Efficacy of olive leaves extract on the outcomes of hospitalized covid The IC50 was 1.7 mg/mL. Heart attack: Dandelion to reduce risk - Express.co.uk AsianScientist (Mar. J Agric Food Chem. The current study focuses on inhibition of the binding of the spike-ACE2 proteins via the spike receptor-binding domain (RBD) in the context of the D614 spike, the D614G mutation, the N501Y mutation, and the triple mutation K417N, E484K, and N501Y. HRI Water Balance Tablets with Dandelion Root, Uva Ursi and Buchu Leaf. False claim: 12 herbs and spices can prevent or treat - Reuters Dandelion root extract is purported to hold many health benefits, such as supplying antioxidants and reducing cholesterol. Common dandelion (Taraxacum officinale) efficiently blocks the interaction between ACE2 cell surface receptor and SARS-CoV-2 spike protein D614, mutants D614G, N501Y, K417N and E484K in vitro, https://doi.org/10.1101/2021.03.19.435959, https://www.biorxiv.org/content/10.1101/2021.03.19.435959v1, https://www.mdpi.com/1424-8247/14/10/1055, 25% of COVID-19 patients have lasting reduction in lung function, Long-awaited findings from the IMMUNEBRIDGE study reveal gaps in SARS-CoV-2 immunity, Rebounding of COVID-19 symptoms and viral load are common among untreated COVID-19 patients, Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants, Following third dose of BNT162b2, adverse events increased in those with prior COVID-19, Study shows antibody-dependent SARS-CoV-2 transmission and pathogenesis. Int J Mol Med. Dandelion is a powerful antioxidant that helps neutralize free radicals. This can lead to a phenomenon. J Ethnopharmacol. Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding. There is a surprising plant which has been shown to be highly effective in keeping the heart healthy and reducing any serious health risks. Miller L. Herbal Medicinals: Selected Clinical Considerations Focusing on Known or Potential Drug-Herb Interactions. We know from other research that dandelion root extract and papaya leaf extract can kill certain types of cancer cells, said Rahmat. Dandelion has a diuretic effect when ingested. Most scientific studies of dandelion have been in animals, not people. Amazing Nutrition. The roots are used in some coffee substitutes, and the flowers are used to make wines. CMML is an aggressive and generally treatment-resistant form of stem cell blood cancer with a median survival rate of 12 to 24 months from diagnosis. In murine models of diet-induced fatty liver disease, dandelion leaf extract exihibited hepatoprotective effects with decreased serum levels of ALT, hepatic TG, and MDA, as well as TNF-alpha and IL-6 expression . Dandelion Root Kills 98% of Cancer Cells in 48 Hours? Dandelion Health benefits, dosage, safety, side-effects, and more "Its just very sad that people do this," Hamm told CBC. This just goes to show that many aren't understanding the COVID-19 is a complication due to SARS-COV-2 reacting with other RNA/DNA virus's that have been dormant in the host, and that those without such infections don't suffer major effects of SARS-COV-2. This was accompanied by anti-inflammatory effects, as reflected by lower levels of the potent inflammatory cytokine interleukin (IL)-6 in the ACE2/TMPRSS2-expressing cells. Tim Heffernan. She noted she did not have a fever or a cough. doi: 10.1016/j.cell.2021.02.037. Sept. 29, 2016, Health Eternally, Scientists Find Root That Kills 98% Of Cancer Cells In Only 48 Hours, Sept. 21, 2016, CBC, Dandelion tea touted as possible cancer killer, Feb. 16, 2012, Ash Publications, Unusual Response of Acute Monocytic Leukemia to Dandelion Root Extract, November 8, 2011, CBC Radio, How a Canadian doctors study on dandelion tea became fake news fodder, Dec. 1, 2017 (or Dec. 2, 2018?? Now Supplements, Silymarin Milk Thistle Extract 300 Mg With Artichoke Options: 3 sizes We use cookies to enhance your experience. Disclaimer. Binding was reduced by 77%, while the high molecular weight fraction alone blocked binding by 63%. The root of the dandelion plant may act as a mild laxative and has been used to improve digestion. Dandelion has widely been touted in naturopathic uses for liver detoxification and. The Health Eternally article said "studies have shown" the extract to kill cancer cells within 48 hours, but it didnt cite specific research. Silwal AP, Thennakoon SKS, Arya SP, Postema RM, Jahan R, Phuoc CMT, Tan X. Theranostics. Digital IDs were given to residents in East Palestine, Ohio, to track long term health problems like difficulty breathing before the Feb. 3 train derailment. Dandelion Leaf B120 Alcohol-Free Herbal Extract Tincture, Concentrated Liquid Drops Natural Dandelion (Taraxacum Officinale) Dried Leaf (4 fl oz) 4 Fl Oz (Pack of 1) 4.8 (21) $3297 ($8.24/Fl Oz) FREE delivery Tue, Feb 21 Only 5 left in stock - order soon. A heart attack occurs when there isa sudden loss of blood supply to the heart, while heart disease is when the heart is unable to pump blood efficiently. Potassium may help the kidney filter toxins more effectively and improve blood flow. Structural and functional properties of SARS-CoV-2 spike protein: Potential antivirus drug development for COVID-19. If you also take prescription diuretics, or other herbs that act as diuretics, you could be at risk of electrolyte imbalances. This site complies with the HONcode standard for trustworthy health information: verify here. Accessibility Arch Intern Med. Free shipping and low prices. Manage blood pressure Dandelions are rich in potassium, which makes them a natural diuretic. Epub 2021 Sep 8. Pomegranate peel extract also showed 74% inhibition of this interaction, and blocking of viral entry into human kidney cells in culture. Studies have examined how effective dandelion root extract is against cancer. In traditional Chinese medicine (TCM), dandelion has been used to treat stomach problems, appendicitis, and breast problems, such as inflammation or lack of milk flow. The cell experiments underline the relevance of this activity. If they repeat this with HEK-293T cells, they will not get the same results. Liji practiced as a full-time consultant in obstetrics/gynecology in a private hospital for a few years following her graduation. New York Eye and Ear Infirmary of Mount Sinai, The Blavatnik Family Chelsea Medical Center, Heart - Cardiology and Cardiovascular Surgery, Mount Sinai Center for Asian Equity and Professional Development, Preparing for Surgery and Major Procedures, Herbs with Similar Side Effects as: Dandelion, Herbs with Similar Warnings as: Dandelion. All rights reserved. 28. After successful treatment of his prostate cancer, the patient began a regimen of consuming papaya leaf extract (pictured left) in 2009. CNN The US Centers for Disease Control and Prevention on Monday placed three new destinations in its "high" risk category for Covid-19, including a North American travel behemoth.. Older people and those with underlying medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, and cancer are more likely to develop serious illness ( WHO, 2020a ). Glycaemic effects of traditional European plant treatments for diabetes. Nicholas,I too am interested in knowing your source.The full text Abstract shows HEK293 A549-hACE2-TMPRSS2 cells from Germany were used in the study [1]. 25. Papaya leaves and their extracts are sold as dietary supplements to improve the immune system and increase platelet counts. As a not-for-profit, full-service, community hospital, Sibley offers medical, surgical, intensive care, obstetric, oncology, orthopaedic and skilled nursing inpatient services and a state-of-the-art 24-hour Emergency Department. (2023, February 23). 19. Findings suggest that 1 in 4 COVID+ . In one study published in the US National Library of Medicine National Institutes of Health, cholesterol-lowering and antioxidant effects of dandelion were analysed. Dandelion | NCCIH News-Medical.Net provides this medical information service in accordance Lu R., Zhao X., Li J., Niu P., Yang B., Wu H., Wang W., Song H., Huang B., Zhu N., et al. Viruses. New. All three have descended from an earlier strain carrying the D614G spike mutation that has rapidly become dominant. A few animal studies also suggest that dandelion might help fight inflammation. Schutz K, Carle R, Schieber A. Taraxacum--a review on its phytochemical and pharmacological profile. However, these uses have not been proven with research. Core Ingredients: Bovines hide collagen peptides, Organic wheat grass, Coconut water powder, Organic alfalfa leaf, Organic kale, Vanilla bean powder, hyaluronic acid, and spinach. ", stated on February 4, 2023 in a Facebook post. We need your help. Most people infected with the COVID-19 virus will experience mild to moderate respiratory illness and recover without requiring special treatment. (SACRAMENTO) With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. In the absence of effective antivirals, its treatment and prevention have been limited to general therapeutic modalities and non-pharmaceutical interventions, despite intensive research aimed at developing better drugs. HRI Water Balance Tablets with Dandelion Root, Uva Ursi and Buchu Leaf GB-2 blocking the interaction between ACE2 and wild type and mutation of spike protein of SARS-CoV-2. If you're feeling bloated, dandelion tea could provide relief because it acts as a diuretic and increases urine output. Anti-Vaxxer Dr Sherri Tenpenny Said She Traveled With COVID Symptoms 10. Official govt docs expose Michelle Obamas 14 year history as a man., "Woody Harrelsons 60 seconds in the middle of his monologue was cut out of the edits released after the show., BREAKING Trump preps Marines to stop presidential coup.. Chang CW, Parsi KM, Somasundaran M, Vanderleeden E, Liu P, Cruz J, Cousineau A, Finberg RW, Kurt-Jones EA. Few contraindications exist but include hypersensitivity, diseases of the biliary tract, or active peptic ulcer disease. Dandelion: Health benefits, research, and side effects - Medical News Today The presence of Vitamin C may account for its reported effectiveness against seasonal colds.. 2022 Oct 10. "Its really unfortunate for patients who believe it. 34. Dandelion flower has antioxidant properties. In traditional Chinese and Native American medicine, dandelion root has long been used to treat stomach and liver conditions. Please use one of the following formats to cite this article in your essay, paper or report: Thomas, Liji. Researchers do not know whether the common dandelion would do the same thing. $16.19 Make It a Routine. 2001;75(2-3):181-184. Says Hitler said Black people are the true Hebrews.. The study concluded that dandelion root and leaf could protect against oxidative stress linked to atherosclerosis and decrease the atherogenic index. A few animal studies also suggest that dandelion might help fight inflammation. 30. Because the potassium in dandelion may impact blood flow and clotting, its best to avoid dandelion tea if youre taking blood-thinner medication.., For the same reason, someone who is taking blood pressure medication should avoid dandelion tea., Clinical Microbiology Reviews: Effects of vitamin a supplementation on immune responses and correlation with clinical outcomes., ESHA Research, Inc., Salem, Oregon: Dandelion., Harvard Health Publishing: Can Vitamin C Prevent a Cold?, Journal of Hypertension: Daily potassium intake and sodium-to-potassium ratio in the reduction of blood pressure: a meta-analysis of randomized controlled trials., Molecules: Purification, Preliminary Characterization and Hepatoprotective Effects of Polysaccharides from Dandelion Root., Penn State Health Milton S. Hershey Medical Center: Dandelion., The Review of Diabetic Studies: The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes., Toxicology and Applied Pharmacology: Risks and Benefits of Commonly used Herbal Medicines in Mxico., University of Michigan Health Library: Dandelion.. On 11th March 2020, coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, was declared as a global pandemic by the World Health Organization (WHO). Case ReportPapaya Leaf/Dandelion Root Extracts May Be Effective in Treating a Deadly Type of Leukemia, Masks are required inside all of our care facilities, COVID-19 testing locations on Maryland.gov. Contact allergy to yarrow and dandelion. -, Berlin D.A., Gulick R.M., Martinez F.J. 2022 Jun 23;14(7):1369. doi: 10.3390/v14071369. Dandelion leaves act as a diuretic, increasing the amount of urine your body makes. Dandelion may also help improve the immune system. Curr Res Chem Biol. 2022;2:100023. doi: 10.1016/j.crchbi.2022.100023. Epub 2022 Mar 14. Molecules | Free Full-Text | Recovery of Polyphenolic Compounds and Pandey told PolitiFact that Canadian regulators approved clinical trials of dandelion root extract for cancer patients as far back as 2013, but researchers had trouble recruiting subjects, and funding dried up. 40. Looking for food delivery from Consult Pharmacy - Jalan SS12/1B? Significance statement SARS-CoV-2 is steadily mutating during continuous transmission among humans. Hundreds of species of dandelion grow in the temperate regions of Europe, Asia, and North America. Dandelion Information | Mount Sinai - New York Dandelion (Taraxacum officinale) is an herb native to Europe. The SARS-CoV-2 virus has undergone a large number of mutations over the pandemic period. doi: 10.1016/j.cell.2021.01.044. Would you like email updates of new search results? "We know from other research that dandelion root extract and papaya leaf extract can kill certain types of cancer cells," said Rahmat. 1800 I Street NW doi: 10.1056/NEJMcp2009575. Infection of the lung cells using SARS-CoV-2 spike pseudotyped lentivirus particles was efficiently prevented by the extract and so was virus-triggered pro-inflammatory interleukin 6 secretion. Purple Perilla Extract. Further sesquiterpenoids and phenolics from Taraxacum officinale. between patient and physician/doctor and the medical advice they may provide. Others may get mouth sores. The leaves, flowers, and root of the plant have traditionally been used in Mexican and other North American medicine. The results also showed that the dandelion extract blocked viral entry into cells, using a pseudotyped lentivirus expressing the SARS-CoV-2 spike, by about 85% at a concentration of 20 mg/ml, and by 70% at half this concentration. Dandelion tea is an excellent source of potassium, a mineral and electrolyte that stimulates the heartbeat. Here we report on the efficacy of common dandelion (Taraxacum officinale) to block protein-protein interaction of SARS-COV-2 spike to the human ACE2 receptor. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Dandelion leaves act as a diuretic, increasing the amount of urine your body makes. This exploits the observed rapid blockade of virus-cell binding and the spike's displacement from already formed spike-ACE2 complexes. The recommended dosage is one to three capsules a day so. 33701 NOTE: Your email address is requested solely to identify you as the sender of this article. 293T/ACE2 cells are transfected to express ACE2, AND HAVE BEEN USED FOR MANY SARS-COV CELL-CELL FUSION AND PSEUDOVIRUS ENTRY INHIBITOR STUDIES [3]. Due to a lack of research on CMML, the optimal treatment regimen remains unclear. Overlay of fluorescence intensity histogram for (, Viral transduction inhibition of A549-hACE2-TMPRSS2 cells by. Serving Size 2 Caplet (s) Servings Per Container 45. Dandelion tea should also be avoided if youre taking antibiotics like Cipro, Levaquin, Noroxin, and others.. Add dandelion to your anti-inflammatory diet: Lab studies have found that compounds in these plants can dial down inflammation. It offers false hope.". In fact, it has been cultivated for its culinary and medicinal benefits for centuries, and modern science has even begun corroborating some of the claims traditionally made about dandelion. There is no recommended dose for artichoke leaf extract in any form. Herbalists today believe that it can aid in the treatment of many ailments, including acne, eczema, high cholesterol, heartburn, gastrointestinal disorders, diabetes, cancer and heart health. Unauthorized use of these marks is strictly prohibited. Careers. Kim HM, Shin HY, Lim KH, el al., Taraxacum officinale inhibits tumor necrosis factor-alpha production from rat astrocytes. High cholesterol: Pain in these two regions are warning signs, New patch could provide early warning of heart attack, Keep your cholesterol and triglyceride levels under control. In an interview with USA Today, Siyaram Pandey, a chemistry and biochemistry professor who co-authored that study, pointed out that this finding was based on a study of cells in a petri dish, not cancer in the human body. What is mRNA? 5 Health Benefits of Dandelions - Cleveland Clinic - Health Essentials on this website is designed to support, not to replace the relationship 04 March 2023. Photo of electric charging station powered by diesel generator is emblematic of the electric vehicle movement. Acta Pharmacol. Fitoterapia. One study showed an increased urine output . Early results indicated the D614G mutation might be associated with higher fatality rates, while the conformational change in the spike protein could lead to higher infectivity. By continuing to browse this site you agree to our use of cookies. Diabetes Res. This paper is flawed, as they used HEK-293 cells, rather than the typically used HEK-293T cells(human kidney cells infected with SV40). Heart attack symptoms: How dangerous is a 'mild heart attack'? They also help your liver filter potentially harmful chemicals out of your food., Dandelion is also a good source of Vitamin C, one of the most helpful vitamins for the immune system. 1986;14 (ISS 4):256-7. (Read more about our partnership with Facebook.). A field of dandelions bloom in a pasture. This may include adverts from us and 3rd parties based on our understanding. Raw dandelion has high levels of vitamin A, vitamins B6 and B9, and vitamin C, making it a plant that reinforces our immune system, helps the body fight off bacteria and toxins, and reduces the risk of cardiovascular disease. The .gov means its official. The catalytic activity of the ACE2 enzyme was unimpaired in the presence of the extract at 24 hours, and cell viability remained unchanged after 84 hours. -. Modern herbal monographs consider the usage of this medicinal plant as safe. They all contain multiple mutations in the ACE2 receptor recognition site of the spike protein, compared to the original Wuhan sequence, which is of great concern, because of their potential for immune escape. Among the conditions dandelions are thought to treat or prevent are: Diabetes 3 Heart disease 1 High blood pressure 1 High cholesterol 1 Liver disease 4 Obesity 5 Rheumatoid arthritis 6 Certain types of cancer 7 To date, there is little evidence that dandelions can treat or prevent any disease. However, herbs can trigger side effects and interact with other herbs, supplements, or medications. Hamm studied the extracts effects on cancer cells and published a case report about a patient who had used the root in a tea with favorable results. The common dandelion (Taraxacum officinale) is a perennial, native to warm temperate zones in the Northern hemisphere, and widely distributed across road margins, fields, gardens and any other open spaces where it is permitted to grow. Enter multiple addresses on separate lines or separate them with commas. 16. However, they may also produce incomplete occlusion of the RBD contact motif, thus preventing spike-ACE2 binding. A Newly Engineered A549 Cell Line Expressing ACE2 and TMPRSS2 Is Highly Permissive to SARS-CoV-2, Including the Delta and Omicron Variants. The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen, has caused over 123.7 million cases and over 2.7 million deaths worldwide. Thus, these cells are permissive to infection by SARS-CoV-2 and Spike-pseudotyped lentiviral particles. To be safe, ask your doctor before taking dandelion if you take any medication. 8. The most abundant phenolic compound was chicoric acid. Platinum Naturals Activ-X Resistance Band - vitamart.ca ", Lula's staff infiltrated and caused damage while the Brazilian Patriots cleaned up., Ray Epps confessed to Jan. 6 Committee he orchestrated attack on Capitol, Tee Higgins "isn't even leaving the hospital till he knows (Damar) Hamlin is OK.", Video shows Sen. John Kennedy telling Secretary of Homeland Security Alejandro Mayorkas, You will be impeached., The Federal Reserve has suspended the availability of new currency.. Int J Oncol. Dandelion extract moves beyond this, with potent inhibition of spike-ACE2 binding, confirmed by inhibition of ACE2-cell surface binding in two different human cell lines. Davies MG, Kersey PJ. The present research investigated the in vivo anti-inflammatory and cardioprotective activities, as well as the antioxidant potential of Taraxacum officinale tincture (TOT), in relation to the polyphenolic composition. Human clinical trials of dandelion root extract as a cancer treatment have been approved, but they havent been able to recruit enough patients. This could be shown for the wild type and mutant forms (D614G, N501Y, and a mix of K417N, E484K, and N501Y) in human HEK293-hACE2 kidney and A549-hACE2-TMPRSS2 lung cells. Dandelion may also help improve the immune system. The inhibitory effects were traced to high molecular weight bioactive compounds in the extract. The claim contains an element of truth, but leaves out important context that could give a different impression. The site is secure. Description. Introduction: Since the emergence of the novel coronavirus, herbal medicine has been considered a treatment for COVID-19 patients. However, not all the animal studies have found a positive effect on blood sugar. 36. official website and that any information you provide is encrypted Common dandelion (Taraxacum officinale) efficiently blocks the This could be shown for the wild type and mutant forms (D614G, N501Y, and a mix of K417N, E484K, and N501Y) in human HEK293-hACE2 kidney and A549-hACE2-TMPRSS2 lung cells.
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